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For Immediate Release
June 23, 2003
Contact: Corinna Kaarlela, News Director
Source: Jennifer O’Brien (415) 476-2557
E-mail: jobrien@pubaff.ucsf.edu
Web: www.ucsf.edu
David A. Kessler Named
New Dean of UCSF School of Medicine
San
Francisco -- David A. Kessler, MD, dean of Yale School of Medicine,
former commissioner of the US Food and Drug Administration, and
one of the nation’s leading public health advocates, today
(June 23) was named dean of the School of Medicine and vice chancellor
for medical affairs at UCSF.
UCSF Chancellor J. Michael Bishop,
MD, announced the appointment.
The appointment of Kessler, 52, is effective
as of September. He succeeds Haile T. Debas, MD, current dean and
vice chancellor for medical affairs. Debas is retiring
after16 years of leadership at UCSF, six years as chair of the Department
of Surgery,
and ten years as dean -- one of which he served simultaneously as
chancellor. Debas
announced his plan to retire last June.
“UCSF is the most dynamic place in American
medicine today,” said Kessler. “Over the last decade
it has led the country, teaching all of us how to educate students,
and how to take down the walls between departments in the basic
sciences. The faculty at UCSF is the most exciting anywhere -- no
where have I seen such an alignment of purpose, such a focused intensity
across a university.”
Kessler called UCSF Mission Bay, a second major
campus now in development that will nearly double UCSF’s teaching
and research space, “a striking accomplishment, unparalleled
in its potential to build interdisciplinary collaboration between
basic and clinical research and to integrate it with state-of-the-art
medical care.”
“We’re very pleased that Dr. Kessler
will be assuming leadership of the UCSF School of Medicine at this
significant point in the school’s history,” said Bishop.
“He is a distinguished public servant and academic leader,
and I believe that his extensive experience in the leadership of
both public and private institutions will serve UCSF well.”
He added, “the school has thrived under
the leadership of Dr. Debas, consistently ranking as one of the
top recipients of National Institutes of Health funding for research
and as one of the top-ranked medical schools.”
Now, said Bishop, the school is poised to move
into a new era of basic and clinical research aimed at gaining further
insights into, and developing therapies for, such diseases as diabetes,
cardiovascular disease, Parkinson’s disease and Alzheimer’s
disease.
“Dr. Kessler has the vision, brilliance
and energy to lead the school in this venture,” he said.
“The School of Medicine is fortunate to
have Dr. Kessler as its next dean. His national stature and demonstrated
courage in advancing the life sciences and public health are noteworthy.
His record of achievements, his intelligence, vision and energy
demonstrate the capacity to lead this wonderful school,” said
Debas.
During his tenure at the Yale School of Medicine,
which began in 1997, Kessler guided the school through a major revitalization
of its academic and research programs and an expansion of its physical
facilities. He recruited a new generation of senior leadership to
many key departments in both the clinical and research arenas, oversaw
the establishment of new basic research programs, developed a new
affiliation agreement between the Yale School of Medicine and the
Yale-New Haven Health System that established a joint investment
in new clinical and research programs by the hospital and the school,
closed the gap in disparity in women faculty’s salaries, and
worked with the faculty to set up the Women’s Health Research
program and the Society of Distinguished Teachers.
He also oversaw the growth and development of
about one million square feet of new or renovated laboratory and
clinical space. He galvanized the medical school to embark on its
largest development project in 70 years, with the construction of
a major new teaching and research complex, The Anlyan Center for
Medical Research and Education, which includes a new magnetic resonance
research center. Part of Yale's expansion also includes a new pharmacology
building and significant renovations of Sterling Hall of Medicine,
the school's major research complex. He also worked with the state
of Connecticut to develop a joint project to significantly expand
the psychiatric research and clinical facility based at Yale. The
funding for the project has been appropriated, and construction
is planned to begin soon.
Kessler, Yale professor of pediatrics, internal
medicine and public health, reflected passionately on his role as
a mentor and teacher at Yale, citing his involvement with students
who went on missions to Kosovo, India and South Africa under the
auspices of the Yale Project for Health Action, and his gratification
in teaching on the hospital wards as an attending pediatrician.
As commissioner of the FDA under Presidents
Bush and Clinton (1990 to 1997), Kessler reinvigorated the agency,
speeding up the drug-approval process in order to get promising
therapies for life-threatening illnesses to patients, including
those with AIDS, improving the medical-device approval process,
instituting preventive controls for food safety, establishing nutrition
labeling for food, establishing new safety regulations for the nation’s
blood supply and developing the MEDWatch program for reporting adverse
events and product problems.
He is most known during those years, however,
for taking on the tobacco industry. He instituted a program to regulate
the marketing and sale of tobacco products to children, and spearheaded
a major investigation that led to the revelation that the tobacco
companies not only had known for 50 years that nicotine was an addictive
drug but that the companies had manipulated the levels of nicotine
in cigarettes. He chronicled this investigation in his book “A
Question of Intent,” which was published in 2001.
Before becoming commissioner of the FDA, Kessler
was medical director at the Hospital of the Albert Einstein College
of Medicine, in New York, and a lecturer on law at Columbia University.
Kessler, who will continue to serve as an attending pediatrician,
at UCSF Children’s Hospital, has published numerous articles
in the New England Journal of Medicine, the Journal of the American
Medical Association, and other medical journals.
He serves on the board of various organizations,
including the Elizabeth Glaser Pediatric AIDS Foundation, of which
he is chairman, Doctors of the World, National Center for Addiction
and Substance Abuse at Columbia University, and the Henry J. Kaiser
Family Foundation.
Kessler’s many honors include receiving
the National Academy of Sciences Public Welfare Medal, in 2001,
and being elected a member of the Institute of Medicine and a fellow
of the American Academy of Arts and Sciences. He has received the
American Cancer Society’s Medal of Honor, the American Heart
Association’s National Public Affairs Special Recognition
Award, the American Federation for AIDS Research Sheldon W. Andelson
Public Policy Achievement Award, and the March of Dimes Franklin
Delano Roosevelt Leadership Award. He also has received 13 honorary
degrees.
He has received a multitude of community and
public service awards in recognition of his contribution on behalf
of public health, including those from the National Association
for the Advancement of Colored People (NAACP), the League of Women
Voters and Common Cause.
Born and raised in New York, Kessler received
his BA degree in 1973, Phi Beta Kappa, from Amherst College. He
earned his MD degree from Harvard Medical School in 1979, did his
internship and medical residency in pediatrics at Johns Hopkins
University School of Medicine, received his JD from The University
of Chicago Law School in 1978, where he was a member of the Law
Review, and received an Advanced Professional Certificate in Management
from New York University Graduate School of Business Administration
in 1986.
Kessler will settle in San Francisco with his
wife, Paulette. Their two children will be attending college.
The recommendation to appoint Kessler was made to the chancellor
by a search committee made up of UCSF faculty and led by Keith Yamamoto,
PhD, UCSF vice dean for research and professor and chair of molecular
and cellular pharmacology.
In appointing Kessler as dean of the UCSF School
of Medicine, the Regents of the University of California approved
a total compensation of $540,000.
UCSF is the only campus in the University of
California’s 10-campus system that is devoted exclusively
to the health sciences. The academic enterprise is composed of schools
of dentistry, medicine, nursing and pharmacy, as well as a graduate
division.
Kessler will lead a faculty that includes 30
researchers who have been elected to the National Academy of Sciences,
one of the highest honors in American science. During the last 13
years, three members of the UCSF faculty have won the Nobel Prize
in Physiology or Medicine, two for discovering that normal genes,
when mutated, can cause cancer, and one for discovering the infectious
protein, known as prion, that causes rare neurodegenerative diseases
in humans and animals, including bovine spongiform encephalopathy,
or “mad cow” disease in cattle.
Photo by Jerry Domian
UCSF School of Medicine Highlights and
Milestones
Highlights:
• Ranks 6th overall among 125 U.S. medical
schools.
• Ranks 4th in research dollars awarded
by the National Institutes of Health.
• Ranks 1st for active patents in the University
of California system.
• Faculty honors: 30 members of the National
Academy of Sciences; 44 members of the Institute of Medicine; 33
members of the American Academy of Arts & Sciences; and 16 who
are Howard Hughes Medical Investigators.
• UCSF School of Medicine is an integral
part of University of California, San Francisco, the only campus
in the 10-campus UC system devoted exclusively to the health sciences.
The UCSF academic enterprise is composed of schools of dentistry,
medicine, nursing and pharmacy, as well as a graduate division.
Milestones:
UCSF School of Medicine has a distinguished
history of groundbreaking medical and scientific discoveries and
accomplishments, including:
• Using microarray technology refined in
a UCSF research lab, provided key supporting evidence that the new,
unknown virus responsible for SARS (severe acute respiratory syndrome)
was a coronavirus—helping to set the foundation for treatment
and containment of the disease. (2003)
• The co-discovery of recombinant DNA techniques
(1974), spawning a revolution in biology, the birth of biotechnology,
which has led to the development of medically useful drug therapies.
• The development of the genetically engineered
hepatitis B vaccine. (1985)
• First to identify the cause of infant
respiratory distress syndrome (1969) and later development of the
revolutionary artificial lung surfactant Exosurf (patented in 1980),
which reduced related infant mortality by half in just two years.
• First successful corrective procedure
on a baby still in the mother’s womb (1981), pioneering the
specialty of fetal diagnosis and treatment and establishing UCSF
internationally as the unparalleled leader in this field.
• The discovery that normal genes, when
mutated, can cause cancer, transforming the way scientists think
about the disease and leading to new strategies for detection and
treatment (1989 Nobel Prize in Physiology or Medicine)
• The discovery of the infectious protein,
known as prion, that causes rare neurodegenerative diseases in humans
and animals, including bovine spongiform encephalopathy, or “mad
cow” disease. (1997 Nobel Prize in Physiology or Medicine)
• The co-discovery of telomerase, an enzyme
that plays a key role in regulating the life span of the cell and
which is now the focus of study as a target for treating cancer
and age-related and degenerative disorders ranging from skin wrinkles
to blindness to cardiovascular disease. (1985)
• The discovery of genes in the round worm
Caenorhabditis elegans that play a key role in regulating the animal’s
aging process. Studies of these genes and the molecular pathways
through which they act have since been shown to affect longevity
in fruit flies and mice and are likely to control life-span in humans.
(1993)
• Co-discovery of HIV (human immunodeficiency
virus), the virus that causes AIDS. (1983)
• First isolation of precursor cells from
mice embryos, a seminal advance laying the groundwork for current
worldwide research on the use of human embryonic stem cells to treat
disease. (1981)
• Gene for human growth hormone cloned,
setting the stage for genetically engineered human growth hormone.
(1979)
• Gene for insulin isolated, leading to
the mass production of recombinant insulin to treat diabetes. (1977)
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